S1: Definition, Uses, and Clinical Overview
S1 most commonly refers to the first sacral level at the base of the spine. It can describe the S1 vertebral segment of the sacrum, the S1 nerve root, or the S1 spinal level used in imaging and procedures. S1 is frequently mentioned in discussions of low back pain, sciatica, and the L5–S1 disc space. Clinicians use “S1” as a precise label for anatomy, symptoms, and treatment targets near the lumbosacral junction.