S2 nerve root: Definition, Uses, and Clinical Overview
The S2 nerve root is a pair of spinal nerve roots that arise from the second sacral spinal segment. It carries nerve signals for sensation and movement between the nervous system and parts of the pelvis and lower limb. Clinicians reference the S2 nerve root when explaining certain patterns of leg pain, numbness, and pelvic symptoms. It is also a common anatomic target in select diagnostic tests, injections, and neuromodulation procedures.